- O-Town
- O-Zone
- O.A.R. (Of A Revolution)
- O.C.
- OAR
- Oasis
- Obie Trice
- Obituary
- Oblivion Dust
- Ocean Blue
- Ocean Colour Scene
- Oceana
- Oceanlab
- Oceansize
- October Tide
- Odyssey
- Of Montreal
- Offspring
- Offspring The
- Ofra Haza
- Oh Land
- Oh, Sleeper
- ohGr
- Ohio Players
- Oi Polloi
- Oi Va Voi
- Oingo Boingo
- OK Go
- Ol Dirty Bastard
- Old 97 s
- Oleander
- Olive
- Oliver Koletzki & Fran
- Oliver Koletzki feat. Fran
- Olivia
- Olivia Newton-john
- Olivia Ong
- Omarion
- OMD
- Omega
- Omega Lithium
- Omnium Gatherum
- On Thorns I Lay
- On-The-Go
- ON/OFF
- One Direction
- One Less Reason
- One Minute Silence
- One Night Only
- One OK Rock